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Tigers ML (-192) @ Cardinals – 7:45 PM ET
Tarik Skubal (2.67 ERA) looks to rebound after his roughest outing of the year, facing a Cards team that feasted on Detroit Monday—but still faces an ace with 71 Ks and elite metrics.

Dodgers -1.5 (-115) vs Diamondbacks – 10:10 PM ET
Yamamoto (2.12 ERA) takes the mound to stop LA’s 4-game skid, while Arizona counters with Ryne Nelson (5.13 ERA) and a bullpen that owns the worst ERA in baseball (5.36).

Under 7.5 (-115) – Guardians @ Twins – 7:40 PM ET
Gavin Williams (3.29 ERA L7 starts) faces Chris Paddack, who’s allowed just 1 ER over his last 14.1 IP. Guardians have averaged just 1 run per game in their last 3.

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All times EST

Cleveland Guardians (25-21) @ Minnesota Twins (26-21) – 6:10 PM ET (Resumption of May 19 Game)
🔹 Bailey Ober (MIN): 3.0 IP, 3.68 ERA — tossed three scoreless before suspension
🔹 At Bat: Kyle Manzardo (CLE) — 1-for-1, .817 OPS
🔍 This is a continuation of Monday’s game, suspended in the 4th with the Twins up 2-1. Ober returns on the mound, and Manzardo is set to bat for Cleveland.

Cincinnati Reds (25-24) @ Pittsburgh Pirates (15-33) – 6:40 PM ET
🔹 Nick Martinez (CIN): 2-4, 3.66 ERA — 2.05 ERA over last 5 starts
🔹 Bailey Falter (PIT): 2-3, 4.02 ERA — 0.54 ERA in last 3 May outings
🔍 Reds have won 5 straight and are 4-0 vs Pittsburgh this season. Martinez has turned a corner, but Falter's been sharp lately. Both teams trending to the under.
Odds: Reds -148, Pirates +124 | Total: 8.0
✅ Best Bet: Under 8.0 (-112)

Chicago Cubs (28-20) @ Miami Marlins (19-27) – 6:40 PM ET
🔹 Jameson Taillon (CHC): 2-3, 4.53 ERA — 8 HR allowed in last 3 starts
🔹 Ryan Weathers (MIA): 1-0, 1.80 ERA — 1 ER over 5 IP in season debut
🔍 Miami has won 4 of 5 and walked off in Game 1. Cubs are road favorites, but Weathers just beat Taillon last week.
Odds: Cubs -142, Marlins +120 | Total: 8.5
✅ Best Bet: Marlins +1.5 (-150)

New York Mets (29-19) @ Boston Red Sox (24-25) – 6:45 PM ET
🔹 Clay Holmes (NYM): 5-2, 3.14 ERA — 3 quality starts in last 5
🔹 Walker Buehler (BOS): 4-1, 4.28 ERA — returns from shoulder issue
🔍 Mets have gone under in 58% of games and are slumping at the plate (.525 OPS last 7 days). Buehler is back without a rehab start, while Boston’s offense thrives late in games.
Odds: Mets -130, Red Sox +110 | Total: 8.5
✅ Best Bet: Under 8.5 (-102)

Atlanta Braves (24-23) @ Washington Nationals (21-27) – 6:45 PM ET
🔹 Mitchell Parker (WSH): 3-3, 4.32 ERA — 4 ER vs ATL last week
🔹 TBD (ATL): Likely Spencer Strider — 5 IP, 2 ER in 2025 debut
🔍 Braves won 3 of 4 in last series vs WSH and just beat Boston 10-4. Atlanta’s rotation still owns elite swing-and-miss stuff, while Washington's offense is streaking.
Odds: Braves -185, Nationals +154 | Total: 8.0
✅ Best Bet: Braves -1.5 (-113)

Houston Astros (25-22) @ Tampa Bay Rays (21-26) – 7:05 PM ET
🔹 Brandon Walter (HOU): MLB debut — 2.97 ERA in Triple-A
🔹 Zack Littell (TB): 3-5, 4.31 ERA — 3.20 ERA over last 4
🔍 Astros are heating up, Rays are 11-18 at home. Houston leads the AL in average vs LHP since 2023, while Tampa’s .203 AVG vs lefties drags them down.
Odds: Astros +110, Rays -130 | Total: 9.0
✅ Best Bet: Under 9.0 (EVEN)

Texas Rangers (25-23) @ New York Yankees (27-19) – 7:05 PM ET
🔹 Patrick Corbin (TEX): 3-2, 3.35 ERA — 9 Ks in last outing
🔹 Will Warren (NYY): 2-2, 4.61 ERA — 9 Ks in 5 IP vs SEA
🔍 Yankees' power vs Corbin’s finesse makes for a clash of styles. Rangers have gone under in 10 of last 12 vs AL East.
Odds: Yankees -205, Rangers +170 | Total: 8.5
✅ Best Bet: Under 8.5 (-108)

San Diego Padres (27-18) @ Toronto Blue Jays (22-24) – 7:07 PM ET
🔹 Dylan Cease (SD): 1-2, 4.60 ERA — 10 Ks in last start
🔹 TBD (TOR): Likely Chris Bassitt — 3.16 ERA, 10 straight 5+ IP starts
🔍 Padres bats are cold (1 run in each of last 3), but still the league’s best road hitting team (.275). Jays have hit .284 vs RHP over last 2 weeks.
Odds: Padres -125, Blue Jays +105 | Total: 8.0
✅ Best Bet: Under 8.0 (-105)

Cleveland Guardians (25-21) @ Minnesota Twins (26-21) – 7:40 PM ET
🔹 Gavin Williams (CLE): 3-2, 4.29 ERA — 3 ER or fewer in 6 of last 7
🔹 Chris Paddack (MIN): 2-3, 4.05 ERA — 1 ER in last 14.1 IP
🔍 Twins have won 13 of 14 and their bullpen has a 0.43 ERA at home this month. Guardians have scored just 3 total runs in their last 3 games.
Odds: Twins -115, Guardians -105 | Total: 7.5
🔥 Top Pick: Under 7.5 (-115)

Seattle Mariners (27-19) @ Chicago White Sox (14-34) – 7:40 PM ET
🔹 Bryse Wilson (CWS): 0-2, 6.00 ERA — 7 ER in last start
🔹 TBD (SEA): Potential bullpen game
🔍 Mariners are riding a 6-game road win streak. Sox have dropped 5 straight and rank last in the AL in OPS.
Odds: Mariners -185, White Sox +154 | Total: 8.5
✅ Best Bet: Mariners -1.5 (-104)

Baltimore Orioles (15-31) @ Milwaukee Brewers (23-25) – 7:40 PM ET
🔹 Keegan Akin (BAL): 0-0, 3.27 ERA — opener role
🔹 Logan Henderson (MIL): 2-0, 2.45 ERA — .184 BAA in first 2 starts
🔍 Orioles have lost 7 straight and are hitting .211 with RISP over last 16 games. Brewers’ bullpen has allowed lowest OPS with 2 strikes since 2023.
Odds: Brewers -135, Orioles +114 | Total: 8.5
✅ Best Bet: Brewers ML (-135)

Detroit Tigers (31-17) @ St. Louis Cardinals (27-21) – 7:45 PM ET
🔹 Tarik Skubal (DET): 4-2, 2.67 ERA — 71 SO, looking to rebound
🔹 Erick Fedde (STL): 3-3, 3.44 ERA — back-to-back scoreless starts
🔍 Tigers are MLB-best 31-17 and get their ace on the mound after a blowout loss. Cards are 16-6 at home and hitting .295 there.
Odds: Tigers -192, Cardinals +160 | Total: 7.5
🔥 Top Pick: Tigers ML (-192)

Philadelphia Phillies (29-18) @ Colorado Rockies (8-39) – 8:40 PM ET
🔹 Jesús Luzardo (PHI): 4-0, 2.00 ERA — dominant with RISP
🔹 Antonio Senzatela (COL): 1-7, 6.39 ERA — 4+ ER in last 4 starts
🔍 Phillies are surging, Rockies are on record-setting losing pace. Luzardo faces a lineup hitting .204 vs LHP this season.
Odds: Phillies -305, Rockies +245 | Total: 11.0
✅ Best Bet: Phillies -1.5 (-135)

Kansas City Royals (27-22) @ San Francisco Giants (28-20) – 9:45 PM ET
🔹 Michael Lorenzen (KC): 3-4, 3.76 ERA — consistent veteran
🔹 Hayden Birdsong (SF): 1-0, 2.31 ERA — MLB starting debut
🔍 Royals lead AL in contact rate vs RHP, but SF's starters have MLB’s best ground-ball rate. Low total reflects recent under trends for both teams.
Odds: Giants -148, Royals +124 | Total: 8.0
✅ Best Bet: Under 8.0 (-115)

Los Angeles Angels (21-25) @ Oakland Athletics (22-26) – 10:05 PM ET
🔹 Kyle Hendricks (LAA): 1-5, 5.18 ERA — 3+ ER in 5 of last 6
🔹 Gunnar Hoglund (OAK): 1-1, 3.78 ERA — allowed 3 HRs in last start
🔍 Angels are showing life with back-to-back wins. A’s have lost 6 straight, outscored 45-11, and own a 7.22 ERA in that span.
Odds: Athletics -166, Angels +140 | Total: 10.5
✅ Best Bet: Over 10.5 (-115)

Arizona Diamondbacks (26-22) @ Los Angeles Dodgers (29-19) – 10:10 PM ET
🔹 Ryne Nelson (ARI): 1-1, 5.13 ERA — rotation spot via injury
🔹 Yoshinobu Yamamoto (LAD): 5-3, 2.12 ERA — 59 SO, 61.7% GB rate
🔍 Dodgers are on a 4-game skid but turn to Yamamoto to stop it. Arizona’s bullpen is worst in MLB (5.36 ERA).
Odds: Dodgers -238, Diamondbacks +195 | Total: 9.5
🔥 Top Pick: Dodgers -1.5 (-115)

Note: The Guardians and Twins are playing a partial doubleheader today. The early game (6:10 PM ET) resumes from a suspended contest with Ober and Manzardo still active. The full game preview above pertains to the scheduled 7:40 PM matchup.

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