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🔥 Top Picks
All times EST
Tigers -1.5 (-105) vs Red Sox – 6:40 PM
Tarik Skubal (2.08 ERA, 60 K) has been lights-out, while Boston’s rookie Hunter Dobbins faces a Tigers lineup averaging 7.3 runs over the past two. Detroit’s 16-5 at home.
Padres -1.5 (-105) vs Angels – 9:40 PM
San Diego’s contact-heavy offense leads MLB in AVG (.265) and gets Kyle Hendricks (5.30 ERA) and an Angels bullpen with a 10.50 ERA in May. Padres are 15-5 at Petco.
Cubs -1.5 (+110) vs Marlins – 7:40 PM
Chicago’s lineup has 16 wins in 18 games with multiple homers. Jameson Taillon (4.53 ERA) faces Ryan Weathers in his 2025 debut. Miami’s 5-14 on the road.
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⚾ Game Previews
📝 Note: We've removed both Twins/Orioles and Phillies/Cardinals matchups from today’s slate. Each team is playing a doubleheader, but Game 1’s in both were already underway by the time we ran the AI — so we chose to exclude both games entirely for clarity and actionable betting purposes. See MLB.com for info on Game 2’s - but we recommend avoiding both for betting purposes.
Milwaukee Brewers (20-23) @ Cleveland Guardians (25-17) – 1:10 PM
🔹 Logan Henderson (MIL): 1-0, 1.35 ERA, 11 SO — limited action
🔹 Gavin Williams (CLE): 3-2, 4.26 ERA, 46 SO — 8 Ks in last start
🔍 Cleveland has back-to-back shutouts and Jose Ramirez on an 8-game hitting streak. Milwaukee’s scored 0 runs in the series and owns the 4th-worst SLG vs RHP.
Odds: Guardians -125, Brewers -105 | Total: 7.5
✅ Best Bet: Under 7.5 (-135)
Arizona Diamondbacks (22-21) @ San Francisco Giants (25-18) – 3:45 PM
🔹 Eduardo Rodriguez (ARI): 1-3, 6.86 ERA, 48 SO — .308 BAA
🔹 Jordan Hicks (SF): 1-4, 5.82 ERA, 40 SO — allowed 3+ ER in 6 of 7 starts
🔍 Arizona leads MLB in runs and late-game scoring, but SF’s bullpen has a 0.67 ERA in late innings. A contrast in strengths with shaky starters on both sides.
Odds: Diamondbacks -108, Giants -112 | Total: 8.0
✅ Best Bet: Over 8 (-115)
New York Yankees (24-18) @ Seattle Mariners (23-18) – 4:10 PM
🔹 Will Warren (NYY): 2-2, 4.75 ERA, 41 SO — coming off best start (7.1 IP, 1 ER)
🔹 Luis Castillo (SEA): 3-3, 3.95 ERA, 33 SO — 2.89 ERA at home
🔍 The Yankees lead MLB in HR and OPS but were held to one run Tuesday. Over has hit in 9 of Seattle’s last 10 home games.
Odds: Yankees -115, Mariners -105 | Total: 8.0
✅ Best Bet: Over 8 (-110)
Boston Red Sox (22-22) @ Detroit Tigers (28-15) – 6:40 PM
🔹 Hunter Dobbins (BOS): 2-1, 2.78 ERA, 19 SO — rookie, 3rd career start
🔹 Tarik Skubal (DET): 4-2, 2.08 ERA, 60 SO — 12 Ks last start, 60:5 K/BB
🔍 Detroit’s won 7 of 10 and is 16-5 at home. Boston’s bullpen collapsed in back-to-back losses.
Odds: Tigers -238, Red Sox +195 | Total: 7.0
🔥 Top Pick: Tigers -1.5 (-105)
Tampa Bay Rays (19-22) @ Toronto Blue Jays (20-21) – 7:07 PM
🔹 Ryan Pepiot (TB): 2-4, 3.86 ERA, 38 SO — solid, low strikeout rate
🔹 Chris Bassitt (TOR): 3-2, 3.35 ERA, 49 SO — Blue Jays 4-game win streak
🔍 Toronto has logged 10+ hits in six straight games and owns the lowest K% vs SPs 3rd time through. Rays have lost 4 of 6.
Odds: Blue Jays -162, Rays +136 | Total: 8.0
✅ Best Bet: Over 8 (-112)
Pittsburgh Pirates (14-29) @ New York Mets (28-15) – 7:10 PM
🔹 Bailey Falter (PIT): 2-3, 4.36 ERA, 31 SO — 1 ER last 13 IP
🔹 Clay Holmes (NYM): 5-1, 2.74 ERA, 44 SO — elite vs LHB
🔍 Mets are 17-4 at home and Pirates rank last in runs (3.05/game). Mets have covered 9 of their last 10 home games on Wednesdays.
Odds: Mets -310, Pirates +250 | Total: 8.0
✅ Best Bet: Under 8 (-112)
Chicago White Sox (13-29) @ Cincinnati Reds (20-23) – 7:14 PM
🔹 Davis Martin (CHW): 1-4, 4.01 ERA, 28 SO — poor run support
🔹 Nick Lodolo (CIN): 3-3, 3.23 ERA, 38 SO — 7 BB in 47.1 IP
🔍 White Sox are 4-17 on the road and last in team batting (.215). Reds favored to rebound after dropping 8 of 10.
Odds: Reds -238, White Sox +195 | Total: 8.5
✅ Best Bet: Reds -1.5 (-105)
Washington Nationals (17-26) @ Atlanta Braves (21-21) – 7:15 PM
🔹 Mitchell Parker (WSH): 3-3, 3.97 ERA, 26 SO — may regress
🔹 Bryce Elder (ATL): 2-2, 4.97 ERA, 30 SO — benefits from elite defense
🔍 Braves have won 2 straight and are 14-6 at home. Nationals on a 7-game skid. Last 6 games in ATL have gone under.
Odds: Braves -166, Nationals +140 | Total: 9.0
✅ Best Bet: Under 9 (-105)
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Miami Marlins (15-26) @ Chicago Cubs (25-18) – 7:40 PM
🔹 Ryan Weathers (MIA): First 2025 start — limited projections
🔹 Jameson Taillon (CHC): 2-2, 4.53 ERA, 35 SO — strong home splits
🔍 Cubs are 16-2 when hitting 2+ HR and 25-18 overall. Marlins are 5-14 on the road and have allowed 8+ runs in 3 of last 4.
Odds: Cubs -225, Marlins +185 | Total: 7.5
🔥 Top Pick: Cubs -1.5 (+110)
Colorado Rockies (7-35) @ Texas Rangers (22-21) – 8:05 PM
🔹 Antonio Senzatela (COL): 1-6, 5.77 ERA, 19 SO — 8 ER in last start
🔹 Patrick Corbin (TEX): 2-2, 3.13 ERA, 20 SO — no more than 2 ER in last 5 starts
🔍 Rangers have won 4 straight and Colorado has 2 road wins all season.
Odds: Rangers -225, Rockies +185 | Total: 9.0
✅ Best Bet: Rangers -1.5 (-110)
Kansas City Royals (25-19) @ Houston Astros (21-20) – 8:10 PM
🔹 Michael Lorenzen (KC): 3-3, 3.57 ERA, 40 SO — 7 scoreless last start
🔹 Colton Gordon (HOU): MLB debut
🔍 Astros have a .984 OPS third time through the order, 14-9 at home. Royals trend under in 11 of last 13 AL night games.
Odds: Astros -125, Royals +105 | Total: 8.5
✅ Best Bet: Under 8.5 (-105)
Los Angeles Angels (17-24) @ San Diego Padres (26-15) – 9:40 PM
🔹 Kyle Hendricks (LAA): 1-4, 5.30 ERA, 21 SO — poor road splits
🔹 Randy Vásquez (SD): 2-3, 3.76 ERA, 18 SO — effective contact manager
🔍 Padres are MLB’s best contact team and face an Angels bullpen with a 10.50 ERA in May. San Diego’s 15-5 at home.
Odds: Padres -185, Angels +154 | Total: 9.0
🔥 Top Pick: Padres -1.5 (-105)
Athletics (22-20) @ Los Angeles Dodgers (27-15) – 10:10 PM
🔹 Gunnar Hoglund (OAK): 1-0, 2.38 ERA, 10 SO — small sample
🔹 Yoshinobu Yamamoto (LAD): 4-3, 1.80 ERA, 53 SO — elite form
🔍 Dodgers are 9-1 as -250 or heavier favorites. A’s crushed LA last night but Yamamoto’s been dominant.
Odds: Dodgers -285, Athletics +230 | Total: 8.5
✅ Best Bet: Dodgers -1.5 (-125)
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